BitterDB ID=16

Magnesium Sulfate

BitterDB id=16
Detailed experimental validation described in the associated resource.

References for the compound bitterness

	Resource	Comment
[1]	Intelmann, D. et al. Three TAS2R Bitter Taste Receptors Mediate the Psychophysical Responses to Bitter Compounds of Hops (Humulus lupulus L.) and Beer. Chemosensory Perception 2, 118-132(2009). springerlink	short-lasting, metallic bitter taste quality perceived mainly at the anterior part of the tongue,
[2]	Behrens M. et al. The human bitter taste receptor TAS2R7 facilitates the detection of bitter salts, Biochemical and Biophysical Research Communications, 2019, Volume 512, Issue 4, Pages 877-881 PubMed 30928101
[3]	Ziegler F. and Behrens M. Bitter taste receptors of the common vampire bat are functional and show conserved responses to metal ions in vitro, Proceedings of the Royal Society B: Biological Sciences, 2021, 288(1947) PubMed 33784867
[4]	Merck Index Monograph Number: 5691
[5]	PubChem 24083

Known bitter receptors targets:

Receptor Name	Effective concentration (μM)	EC50 (μM)	References
hTas2r7	10000.0	14900.0	PubMed:30928101
droTas2r7	100000.0		PubMed:33784867

Sensory data about the compound bitterness:

Sensory Data Type	Value	Reference
Bitter recognition threshold	166 [mM]	Reference

Properties:

Mol. Weight: 120.3700 [g/mol]	AlogP(octanol-water): -1.71880
# Hydrogen Bond Donor: 0	# Hydrogen Bond Acceptor: 4
# Aromatic Rings: 0	# Rings: 0
# Rotatable Bonds: 0

Identifiers:

CAS Registry Number: 7487-88-9

Formula: MgO4S

IUPAC Systematic Name:

SMILES:

Canonical SMILES:

InChI Key: CSNNHWWHGAXBCP-UHFFFAOYSA-L

Links:

[1]	PubChem	24083
[2]	DrugBank	DB00653