BitterDB

hTAS2R50 - Human (Homo sapiens) Taste Receptor Type 2 Member 50

Alternative Names: Taste receptor type 2 member 51 T2R51

Links and Citations:

UniProt	P59544
GPCRDB	t2r50_human
GeneCards	TAS2R50
The Human Protein Atlas	ENSG00000212126-TAS2R50
IUPHAR/BPS	link

Properties

Organism: Human
Location: chr12:11,138,512-11,139,511 UCSC
Number of known ligands: 4
MW: 34,558 (Da)
Sequence:

MITFLYIFFSILIMVLFVLGNFANGFIALVNFIDWVKRKK ISSADQILTALAVSRIGLLWALLLNWYLTVLNPAFYSVEL RITSYNAWVVTNHFSMWLAANLSIFYLLKIANFSNLLFLH LKRRVRSVILVILLGTLIFLVCHLLVANMDESMWAEEYEG NMTGKMKLRNTVHLSYLTVTTLWSFIPFTLSLISFLMLIC SLCKHLKKMQLHGEGSQDLSTKVHIKALQTLISFLLLCAI FFLFLIVSVWSPRRLRNDPVVMVSKAVGNIYLAFDSFILI WRTKKLKHTFLLILCQIRC

Known Ligands

Download SDF file of selected compounds.

	Amarogentin
	Andrographolide
	Dehydroandrographolide
	Amarogentin

Experimental/ Computational 3D structures

Here are links to the 3D structures of the receptors. If an experimental structure is available, it is recommended to use the RCSB PDB link. Otherwise, you can use the computationally predicted AlphaFold 3D model.

RCSB PDB: link

AlphaFold: link

Protein Diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table

Receptor	Location	BW number	Residue	MAF	dbSNP
TAS2R50		5.66	C203Y	0.4103	rs1376251

Known Mutations Table

No mutations were reported yet.

Known SNP Table

Receptor	Location	BW number	Residue	MAF	dbSNP
hTAS2R50		5.66	C203Y	0.4103	rs1376251